PrimePCR™ SYBR® Green Assay: TIRAP, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCEP0035601

List Price:    $179.00
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PrimePCR™ PreAmp for SYBR® Green Assay: TIRAP, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: TIRAP, Human
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0034776
Assay Design:   Exonic
Chromosome Location:   11:126159560-126159700question
Amplicon Length:   111
Splice Variants Targeted:   ENST00000392678 ENST00000392680

Gene Information

The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs) which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B MAPK1 MAPK3 and JNK which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however not all variants have been fully described. [provided by RefSeq Jul 2008]

Gene Symbol:   TIRAP
Gene Name:   toll-interleukin 1 receptor (TIR) domain containing adaptor protein
Aliases:   FLJ42305, Mal, wyatt
RefSeq:   NC_000011.9 NG_011523.1 NT_033899.8
Ensembl:   ENSG00000150455
Entrez:   114609
Chromosome Mapping:   11q24.2

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