PrimePCR™ SYBR® Green Assay: EIF4EBP1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0005914
Assay Design:   Intron-spanning
Chromosome Location:   8:37914736-37917495question
Amplicon Length:   87
Splice Variants Targeted:   ENST00000338825

Gene Information

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq Jul 2008]

Gene Symbol:   EIF4EBP1
Gene Name:   eukaryotic translation initiation factor 4E binding protein 1
Aliases:   4E-BP1, 4EBP1, BP-1, MGC4316, PHAS-I
RefSeq:   NC_000008.10 NT_167187.1
Ensembl:   ENSG00000187840
Entrez:   1978
Chromosome Mapping:   8p12

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