PrimePCR™ SYBR® Green Assay: GADD45B, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0002576
Assay Design:   Exonic
Chromosome Location:   19:2478010-2478188question
Amplicon Length:   149
Splice Variants Targeted:   ENST00000215631

Gene Information

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq Jul 2008]

Gene Symbol:   GADD45B
Gene Name:   growth arrest and DNA-damage-inducible, beta
Aliases:   DKFZp566B133, GADD45BETA, MYD118
RefSeq:   NC_000019.9 NT_011255.14
Ensembl:   ENSG00000099860
Entrez:   4616
Chromosome Mapping:   19p13.3

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