PrimePCR™ SYBR® Green Assay: GDNF, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0003168
Assay Design:   Exonic
Chromosome Location:   5:37815865-37815981question
Amplicon Length:   87
Splice Variants Targeted:   ENST00000326524 ENST00000515058 ENST00000427982 ENST00000381826 ENST00000344622

Gene Information

This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq Jun 2010]

Gene Symbol:   GDNF
Gene Name:   glial cell derived neurotrophic factor
Aliases:   ATF1, ATF2, HFB1-GDNF, HSCR3
RefSeq:   NC_000005.9 NG_011675.2 NT_006576.16
Ensembl:   ENSG00000168621
Entrez:   2668
Chromosome Mapping:   5p13.1-p12

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