PrimePCR™ SYBR® Green Assay: HLA-DMA, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCEP0040016

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0037293
Assay Design:   exonic
Chromosome Location:   6:32918489-32920727question
Amplicon Length:   63
Splice Variants Targeted:   ENST00000383227 ENST00000383230 ENST00000412394 ENST00000418042 ENST00000293677 ENST00000452330 ENST00000434337 ENST00000433630 ENST00000437285 ENST00000319888 ENST00000576251 ENST00000574538 ENST00000391713 ENST00000592355 ENST00000587340 ENST00000420931 ENST00000439054 ENST00000456486 ENST00000441171 ENST00000419041 ENST00000441375 ENST00000416806 ENST00000419231 ENST00000451148 ENST00000453490 ENST00000422196 ENST00000416297 ENST00000452434 ENST00000450601 ENST00000454298 ENST00000458066 ENST

Gene Information

HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB) both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes dendritic cells macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide exons 2 and 3 encode the two extracellular domains exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq Jul 2008]

Gene Symbol:   HLA-DMA
Gene Name:   major histocompatibility complex, class II, DM alpha
Aliases:   D6S222E, DMA, HLADM, RING6
RefSeq:   NC_000006.11 NG_012006.1 NT_007592.15 NT_113891.2 NT_167244.1 NT_167245.1 NT_167246.1 NT_167247.1 NT_167248.1 NT_167249.1
Ensembl:   ENSG00000204257
Entrez:   3108
Chromosome Mapping:   6p21.3

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