PrimePCR™ SYBR® Green Assay: ARNT, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCIP0027033

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0009053
Assay Design:   Intron-spanning
Chromosome Location:   1:150804824-150807099question
Amplicon Length:   108
Splice Variants Targeted:   ENST00000358595 ENST00000354396 ENST00000515192 ENST00000505755 ENST00000394700 ENST00000368975

Gene Information

The aryl hydrocarbon (Ah) receptor is involved in the induction of several enzymes that participate in xenobiotic metabolism. The ligand-free cytosolic form of the Ah receptor is complexed to heat shock protein 90. Binding of ligand which includes dioxin and polycyclic aromatic hydrocarbons results in translocation of the ligand-binding subunit only to the nucleus. Induction of enzymes involved in xenobiotic metabolism occurs through binding of the ligand-bound Ah receptor to xenobiotic responsive elements in the promoters of genes for these enzymes. This gene encodes a protein that forms a complex with the ligand-bound Ah receptor and is required for receptor function. The encoded protein has also been identified as the beta subunit of a heterodimeric transcription factor hypoxia-inducible factor 1. A t(1;12)(q21;p13) translocation which results in a TEL-ARNT fusion protein is associated with acute myeloblastic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq Oct 2010]

Gene Symbol:   ARNT
Gene Name:   aryl hydrocarbon receptor nuclear translocator
Aliases:   HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2
RefSeq:   NG_011848.1 NC_000001.10 NT_004487.19
Ensembl:   ENSG00000143437
Entrez:   405
Chromosome Mapping:   1q21

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