PrimePCR™ SYBR® Green Assay: TLR5, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCIP0027150

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0009328
Assay Design:   Intron-spanning
Chromosome Location:   1:223308154-223310611question
Amplicon Length:   115
Splice Variants Targeted:   ENST00000366881 ENST00000540964

Gene Information

This gene encodes a member of the toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus and susceptibility to Legionnaire disease.[provided by RefSeq Dec 2009]

Gene Symbol:   TLR5
Gene Name:   toll-like receptor 5
Aliases:   FLJ10052, MGC126430, MGC126431, SLEB1, TIL3
RefSeq:   NC_000001.10 NG_016244.1 NT_167186.1
Ensembl:   ENSG00000187554
Entrez:   7100
Chromosome Mapping:   1q41-q42

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