PrimePCR™ SYBR® Green Assay: CASR, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0016737
Assay Design:   Intron-spanning
Chromosome Location:   3:121973173-121975975question
Amplicon Length:   67
Splice Variants Targeted:   ENST00000490131 ENST00000498619 ENST00000296154

Gene Information

The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia familial isolated hypoparathyroidism and neonatal severe primary hyperparathyroidism. [provided by RefSeq Jul 2008]

Gene Symbol:   CASR
Gene Name:   calcium-sensing receptor
Aliases:   CAR, EIG8, FHH, FIH, GPRC2A, HHC, HHC1, MGC138441, NSHPT, PCAR1
RefSeq:   NC_000003.11 NG_009058.1 NT_005612.16
Ensembl:   ENSG00000036828
Entrez:   846
Chromosome Mapping:   3q13

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