PrimePCR™ SYBR® Green Assay: PRKAA2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Recommended - best efficiency

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0016799
Assay Design:   Intron-spanning
Chromosome Location:   1:57171765-57173191question
Amplicon Length:   141
Splice Variants Targeted:   ENST00000371244

Gene Information

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses AMPK is activated and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR) key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq Jul 2008]

Gene Symbol:   PRKAA2
Gene Name:   protein kinase, AMP-activated, alpha 2 catalytic subunit
Aliases:   AMPK, AMPK2, PRKAA
RefSeq:   NC_000001.10 NT_032977.9
Ensembl:   ENSG00000162409
Entrez:   5563
Chromosome Mapping:   1p31

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