PrimePCR™ SYBR® Green Assay: MAPK10, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCIP0040609

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0037886
Assay Design:   Intron-spanning
Chromosome Location:   4:87115513-87275742question
Amplicon Length:   78
Splice Variants Targeted:   ENST00000395169 ENST00000359221 ENST00000361569 ENST00000395166 ENST00000512017 ENST00000512564 ENST00000511167 ENST00000509464 ENST00000506773 ENST00000512689 ENST00000502302 ENST00000513186 ENST00000449047 ENST00000395161

Gene Information

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation differentiation transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2 a receptor-regulated MAP kinase scaffold protein is found to interact with and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate and inhibit the activity of this kinase which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq Jul 2008]

Gene Symbol:   MAPK10
Gene Name:   mitogen-activated protein kinase 10
Aliases:   FLJ12099, FLJ33785, JNK3, JNK3A, MGC50974, PRKM10, p493F12, p54bSAPK
RefSeq:   NC_000004.11 NG_013325.1 NT_016354.19
Ensembl:   ENSG00000109339
Entrez:   5602
Chromosome Mapping:   4q22.1-q23

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