PrimePCR™ SYBR® Green Assay: IL6ST, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCIP0026506

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0007540
Assay Design:   Intron-spanning
Chromosome Location:   5:55265634-55272119question
Amplicon Length:   97
Splice Variants Targeted:   ENST00000381298 ENST00000381293 ENST00000522633 ENST00000336909 ENST00000381294 ENST00000542298 ENST00000381287 ENST00000536319

Gene Information

The protein encoded by this gene is a signal transducer shared by many cytokines including interleukin 6 (IL6) ciliary neurotrophic factor (CNTF) leukemia inhibitory factor (LIF) and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6 a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq Jul 2010]

Gene Symbol:   IL6ST
Gene Name:   interleukin 6 signal transducer (gp130, oncostatin M receptor)
Aliases:   CD130, CDW130, DKFZp564F053, GP130, IL-6RB
RefSeq:   NC_000005.9 NT_006713.15
Ensembl:   ENSG00000134352
Entrez:   3572
Chromosome Mapping:   5q11

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