PrimePCR™ SYBR® Green Assay: BARD1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

List Price:    $179.00
Your Price:   Log In
 
Add to Custom Plate

Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0011023
Assay Design:   Intron-spanning
Chromosome Location:   2:215609835-215610511question
Amplicon Length:   85
Splice Variants Targeted:   ENST00000260947 ENST00000421162 ENST00000449967

Gene Information

This gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1 implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. [provided by RefSeq Jul 2008]

Gene Symbol:   BARD1
Gene Name:   BRCA1 associated RING domain 1
Aliases:   Not Available
RefSeq:   NC_000002.11 NG_012047.1 NT_005403.17
Ensembl:   ENSG00000138376
Entrez:   580
Chromosome Mapping:   2q34-q35

[ Close ]
Click here to print
[ Close ]
Click here to print
 

undefined

undefined

My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

undefined

undefined

undefined

undefined

undefined

undefined

undefined

undefined