PrimePCR™ SYBR® Green Assay: GRIA4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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PrimePCR™ PreAmp for SYBR® Green Assay: GRIA4, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: GRIA4, Human
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0009139
Assay Design:   Intron-spanning
Chromosome Location:   11:105769124-105774599question
Amplicon Length:   60
Splice Variants Targeted:   ENST00000282499 ENST00000393127 ENST00000539249 ENST00000530497 ENST00000525187 ENST00000428631 ENST00000393125

Gene Information

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq Jul 2008]

Gene Symbol:   GRIA4
Gene Name:   glutamate receptor, ionotrophic, AMPA 4
Aliases:   GLUR4, GLUR4C, GLURD, GluA4
RefSeq:   NC_000011.9 NT_033899.8
Ensembl:   ENSG00000152578
Entrez:   2893
Chromosome Mapping:   11q22

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