PrimePCR™ SYBR® Green Assay: KCNQ1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCIP0026485

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0007481
Assay Design:   Intron-spanning
Chromosome Location:   11:2799218-2869045question
Amplicon Length:   69
Splice Variants Targeted:   ENST00000155840 ENST00000335475

Gene Information

This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome) Jervell and Lange-Nielsen syndrome and familial atrial fibrillation. This gene exhibits tissue-specific imprinting with preferential expression from the maternal allele in some tissues and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS) and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq Aug 2011]

Gene Symbol:   KCNQ1
Gene Name:   potassium voltage-gated channel, KQT-like subfamily, member 1
Aliases:   ATFB1, ATFB3, FLJ26167, JLNS1, KCNA8, KCNA9, KVLQT1, Kv1.9, Kv7.1, LQT, LQT1, RWS, SQT2, WRS
RefSeq:   NG_016178.1 NC_000011.9 NG_008935.1 NT_009237.18
Ensembl:   ENSG00000053918
Entrez:   3784
Chromosome Mapping:   11p15.5

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