PrimePCR™ SYBR® Green Assay: RRM2B, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCIP0028530

List Price:    $179.00
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PrimePCR™ PreAmp for SYBR® Green Assay: RRM2B, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: RRM2B, Human
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0012634
Assay Design:   Intron-spanning
Chromosome Location:   8:103237133-103238186question
Amplicon Length:   125
Splice Variants Targeted:   ENST00000251810 ENST00000522368 ENST00000395912 ENST00000535248

Gene Information

This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome autosomal dominant progressive external ophthalmoplegia-5 and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq Feb 2010]

Gene Symbol:   RRM2B
Gene Name:   ribonucleotide reductase M2 B (TP53 inducible)
Aliases:   DKFZp686M05248, MGC102856, MGC42116, MTDPS8A, MTDPS8B, P53R2
RefSeq:   NC_000008.10 NT_008046.16 NG_016617.1
Ensembl:   ENSG00000048392
Entrez:   50484
Chromosome Mapping:   8q23.1

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