PrimePCR™ SYBR® Green Assay: GCK, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCIP0029551

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0014780
Assay Design:   Intron-spanning
Chromosome Location:   7:44187367-44189572question
Amplicon Length:   140
Splice Variants Targeted:   ENST00000403799 ENST00000395796 ENST00000345378 ENST00000437084

Gene Information

Hexokinases phosphorylate glucose to produce glucose-6-phosphate the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM) maturity onset diabetes of the young type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq Apr 2009]

Gene Symbol:   GCK
Gene Name:   glucokinase (hexokinase 4)
Aliases:   FGQTL3, GK, GLK, HHF3, HK4, HKIV, HXKP, LGLK, MODY2
RefSeq:   NC_000007.13 NG_008847.1 NT_007819.17
Ensembl:   ENSG00000106633
Entrez:   2645
Chromosome Mapping:   7p15.3-p15.1

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