PrimePCR™ SYBR® Green Assay: STAT6, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Recommended - best coverage

List Price:    $179.00
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PrimePCR™ PreAmp for SYBR® Green Assay: STAT6, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: STAT6, Human
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0005014
Assay Design:   Exonic
Chromosome Location:   12:57501956-57502058question
Amplicon Length:   73
Splice Variants Targeted:   ENST00000542516 ENST00000555849 ENST00000556259 ENST00000553499 ENST00000553397 ENST00000554663 ENST00000554825 ENST00000557635 ENST00000553275 ENST00000535201 ENST00000542721 ENST00000300134 ENST00000543873 ENST00000556155 ENST00000454075

Gene Information

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L) which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells expression of cell surface markers and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq May 2010]

Gene Symbol:   STAT6
Gene Name:   signal transducer and activator of transcription 6, interleukin-4 induced
Aliases:   D12S1644, IL-4-STAT, STAT6B, STAT6C
RefSeq:   NC_000012.11 NT_029419.12 NG_021272.1
Ensembl:   ENSG00000166888
Entrez:   6778
Chromosome Mapping:   12q13

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