PrimePCR™ SYBR® Green Assay: GNRHR, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCEP0039133

List Price:    $179.00
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PrimePCR™ PreAmp for SYBR® Green Assay: GNRHR, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: GNRHR, Human
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0036409
Assay Design:   exonic
Chromosome Location:   4:68619691-68619814question
Amplicon Length:   94
Splice Variants Targeted:   ENST00000226413 ENST00000420975

Gene Information

This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes breast ovary and prostate. Following binding of gonadotropin-releasing hormone the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   GNRHR
Gene Name:   gonadotropin-releasing hormone receptor
Aliases:   GNRHR1, GRHR, LHRHR, LRHR
RefSeq:   NC_000004.11 NG_009293.1 NT_022778.16
Ensembl:   ENSG00000109163
Entrez:   2798
Chromosome Mapping:   4q21.2

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