PrimePCR™ SYBR® Green Assay: HNMT, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCEP0040406

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0037683
Assay Design:   exonic
Chromosome Location:   2:138722052-138722168question
Amplicon Length:   87
Splice Variants Targeted:   ENST00000410115 ENST00000329366 ENST00000280097 ENST00000280096

Gene Information

In mammals histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   HNMT
Gene Name:   histamine N-methyltransferase
Aliases:   HMT, HNMT-S1, HNMT-S2
RefSeq:   NC_000002.11 NT_022135.16 NG_012966.1
Ensembl:   ENSG00000150540
Entrez:   3176
Chromosome Mapping:   2q22.1

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