PrimePCR™ SYBR® Green Assay: GRM2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCEP0040501

List Price:    $179.00
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PrimePCR™ PreAmp for SYBR® Green Assay: GRM2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: GRM2, Human
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0037778
Assay Design:   exonic
Chromosome Location:   3:51752078-51752210question
Amplicon Length:   103
Splice Variants Targeted:   ENST00000395052 ENST00000442933

Gene Information

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology putative signal transduction mechanisms and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4 GRM6 GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   GRM2
Gene Name:   glutamate receptor, metabotropic 2
Aliases:   GLUR2, GPRC1B, MGLUR2, mGlu2
RefSeq:   NC_000003.11 NT_022517.18
Ensembl:   ENSG00000164082
Entrez:   2912
Chromosome Mapping:   3p21.2

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