PrimePCR™ SYBR® Green Assay: MVK, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0050602

List Price:    $179.00
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PrimePCR™ PreAmp for SYBR® Green Assay: MVK, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: MVK, Human
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0043340
Assay Design:   exonic
Chromosome Location:   12:110013815-110013934question
Amplicon Length:   90
Splice Variants Targeted:   ENST00000539335 ENST00000546277 ENST00000228510 ENST00000392727 ENST00000539575 ENST00000541384

Gene Information

This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate and mevalonate kinase a key early enzyme in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria a disease characterized psychomotor retardation failure to thrive hepatosplenomegaly anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome a disorder characterized by recurrent episodes of fever associated with lymphadenopathy arthralgia gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   MVK
Gene Name:   mevalonate kinase
Aliases:   FLJ96772, LRBP, MK, MVLK
RefSeq:   NC_000012.11 NG_007096.1 NG_007702.1 NT_009775.17
Ensembl:   ENSG00000110921
Entrez:   4598
Chromosome Mapping:   12q24

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