PrimePCR™ SYBR® Green Assay: MAPK14, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCEP0050679

List Price:    $179.00
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PrimePCR™ PreAmp for SYBR® Green Assay: MAPK14, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: MAPK14, Human
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0043417
Assay Design:   exonic
Chromosome Location:   6:36020486-36020597question
Amplicon Length:   82
Splice Variants Targeted:   ENST00000229795 ENST00000229794 ENST00000468133 ENST00000310795 ENST00000472333

Gene Information

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation differentiation transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs) or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2 MEF2C and MAX cell cycle regulator CDC25B and tumor suppressor p53 which suggest the roles of this kinase in stress related transcription and cell cycle regulation as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq Jul 2008]

Gene Symbol:   MAPK14
Gene Name:   mitogen-activated protein kinase 14
Aliases:   CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA
RefSeq:   NC_000006.11 NT_007592.15
Ensembl:   ENSG00000112062
Entrez:   1432
Chromosome Mapping:   6p21.3-p21.2

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