PrimePCR™ SYBR® Green Assay: GRM6, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCEP0050742

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0043480
Assay Design:   exonic
Chromosome Location:   5:178416292-178417602question
Amplicon Length:   95
Splice Variants Targeted:   ENST00000517717 ENST00000231188

Gene Information

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology putative signal transduction mechanisms and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4 GRM6 GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq Feb 2012]

Gene Symbol:   GRM6
Gene Name:   glutamate receptor, metabotropic 6
Aliases:   CSNB1B, DKFZp686H1993, GPRC1F, MGLUR6, mGlu6
RefSeq:   NC_000005.9 NG_008105.1 NT_023133.13
Ensembl:   ENSG00000113262
Entrez:   2916
Chromosome Mapping:   5q35

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