PrimePCR™ SYBR® Green Assay: FANCD2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCEP0052466

List Price:    $179.00
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PrimePCR™ PreAmp for SYBR® Green Assay: FANCD2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: FANCD2, Human
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0045205
Assay Design:   exonic
Chromosome Location:   3:10074630-10076380question
Amplicon Length:   67
Splice Variants Targeted:   ENST00000287647 ENST00000419585 ENST00000431693 ENST00000383807 ENST00000383806

Gene Information

The Fanconi anemia complementation group (FANC) currently includes FANCA FANCB FANCC FANCD1 (also called BRCA2) FANCD2 FANCE FANCF FANCG FANCI FANCJ (also called BRIP1) FANCL FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability hypersensitivity to DNA crosslinking agents increased chromosomal breakage and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   FANCD2
Gene Name:   Fanconi anemia, complementation group D2
Aliases:   DKFZp762A223, FA-D2, FA4, FACD, FAD, FAD2, FANCD, FLJ23826
RefSeq:   NC_000003.11 NG_007311.1 NT_022517.18
Ensembl:   ENSG00000144554
Entrez:   2177
Chromosome Mapping:   3p26

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