PrimePCR™ SYBR® Green Assay: NR1H4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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PrimePCR™ PreAmp for SYBR® Green Assay: NR1H4, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: NR1H4, Human
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0008044
Assay Design:   Intron-spanning
Chromosome Location:   12:100955726-100957079question
Amplicon Length:   72
Splice Variants Targeted:   ENST00000548884 ENST00000392986 ENST00000549996 ENST00000551379 ENST00000188403

Gene Information

This gene encodes a ligand-activated transcription factor which shares structural features in common with nuclear hormone receptor family such as a DNA-binding domain that targets the receptor to specific DNA sequences and a ligand-binding domain which interacts directly with the ligand and contains a ligand-dependent transcriptional activation domain. This protein functions as a receptor for bile acids and when bound to bile acids regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq Aug 2011]

Gene Symbol:   NR1H4
Gene Name:   nuclear receptor subfamily 1, group H, member 4
Aliases:   BAR, FXR, HRR-1, HRR1, MGC163445, RIP14
RefSeq:   NC_000012.11 NT_029419.12
Ensembl:   ENSG00000012504
Entrez:   9971
Chromosome Mapping:   12q23.1

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