PrimePCR™ SYBR® Green Assay: ANGPTL4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCIP0027370

List Price:    $179.00
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PrimePCR™ PreAmp for SYBR® Green Assay: ANGPTL4, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: ANGPTL4, Human
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0009887
Assay Design:   Intron-spanning
Chromosome Location:   19:8434135-8435993question
Amplicon Length:   106
Splice Variants Targeted:   ENST00000301455 ENST00000541807

Gene Information

This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis lipid metabolism and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq Jul 2008]

Gene Symbol:   ANGPTL4
Gene Name:   angiopoietin-like 4
Aliases:   ANGPTL2, ARP4, FIAF, HFARP, NL2, PGAR, pp1158
RefSeq:   NC_000019.9 NT_077812.2 NG_012169.1
Ensembl:   ENSG00000167772
Entrez:   51129
Chromosome Mapping:   19p13.3

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