PrimePCR™ SYBR® Green Assay: CDH1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Recommended - best coverage

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0015365
Assay Design:   Intron-spanning
Chromosome Location:   16:68849626-68853255question
Amplicon Length:   80
Splice Variants Targeted:   ENST00000261769 ENST00000268794 ENST00000379120 ENST00000422392

Gene Information

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric breast colorectal thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation invasion and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq Jul 2008]

Gene Symbol:   CDH1
Gene Name:   cadherin 1, type 1, E-cadherin (epithelial)
RefSeq:   NM_004360
Ensembl:   ENSG00000039068
Entrez:   999
Chromosome Mapping:   chr16:68771194-68869444

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