PrimePCR™ SYBR® Green Assay: Psen2, Mouse

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qMmuCIP0031746

List Price:    $179.00
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PrimePCR™ PreAmp for SYBR® Green Assay: Psen2, Mouse
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: Psen2, Mouse
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qMmuCID0006082
Assay Design:   Intron-spanning
Chromosome Location:   1:180235168-180238912question
Amplicon Length:   120
Splice Variants Targeted:   ENSMUST00000111108 ENSMUST00000111106 ENSMUST00000010753 ENSMUST00000111105 ENSMUST00000111104

Gene Information

This gene encodes a member of the presenilin family. Presenilins are catalytic components of the multi-subunit gamma-secretase complex which mediates critical cellular processes through cleavage of type I transmembrane proteins including Notch receptors and the amyloid precursor protein. The encoded protein contains eight transmembrane domains and is localized to the endoplasmic reticulum where it may play a role in calcium homeostasis. Following assembly of the gamma-secretase complex the encoded protein is cleaved into N- and C-terminal fragments and the activated complex is released from the endoplasmic reticulum. Inactivation of this gene results in impaired synaptic function in a mouse model for Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq Apr 2011]

Gene Symbol:   Psen2
Gene Name:   Presenilin 2
Aliases:   ALG-3, Ad4h, Alg3, PS-2, PS2, Psnl2, STM2
RefSeq:   NC_000067.6 NT_039185.8
Ensembl:   ENSMUSG00000010609
Entrez:   19165
Chromosome Mapping:   1 H4|1 101.0 cM

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