PrimePCR™ SYBR® Green Assay: Aco1, Rat

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qRnoCID0001184
Assay Design:   intron_spanning
Chromosome Location:   5:61018857-61020415question
Amplicon Length:   119
Splice Variants Targeted:   ENSRNOT00000008337

Gene Information

This gene encodes a member of the aconitase/IPM isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Depending on iron levels in the cytosol, the encoded protein can function as either an aconitase enzyme or as an mRNA binding protein. When cellular iron levels are high, the encoded protein functions as an aconitase, an essential enzyme in the TCA cycle that catalyzes the conversion of citrate to isocitrate. When cellular iron levels are low, the encoded protein regulates iron uptake and utilization by binding to iron-responsive elements in the untranslated regions of mRNAs for genes involved in iron metabolism [provided by RefSeq, Jan 2014]

Gene Symbol:   Aco1
Gene Name:   Cytoplasmic aconitate hydratase
Aliases:   Not Available
RefSeq:   NM_017321
Ensembl:   ENSRNOG00000005849
Entrez:   50655
Chromosome Mapping:   5q22

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