PrimePCR™ SYBR® Green Assay: PRKACB, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0013352
Assay Design:   Intron-spanning
Chromosome Location:   1:84662373-84663476question
Amplicon Length:   88
Splice Variants Targeted:   ENST00000370689 ENST00000370688 ENST00000370685 ENST00000370684 ENST00000432111 ENST00000450730 ENST00000370680 ENST00000413538 ENST00000417530 ENST00000394839 ENST00000394838 ENST00000370682 ENST00000370679 ENST00000370681

Gene Information

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Several alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq Jun 2011]

Gene Symbol:   PRKACB
Gene Name:   protein kinase, cAMP-dependent, catalytic, beta
Aliases:   DKFZp781I2452, MGC41879, MGC9320, PKACB
RefSeq:   NC_000001.10 NT_032977.9
Ensembl:   ENSG00000142875
Entrez:   5567
Chromosome Mapping:   1p31.1

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