PrimePCR™ SYBR® Green Assay: CASP2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0008805
Assay Design:   Intron-spanning
Chromosome Location:   7:142991814-142997070question
Amplicon Length:   78
Splice Variants Targeted:   ENST00000310447 ENST00000392923

Gene Information

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways cell cycle maintenance and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq Jan 2011]

Gene Symbol:   CASP2
Gene Name:   caspase 2, apoptosis-related cysteine peptidase
Aliases:   CASP-2, ICH1, NEDD-2, NEDD2
RefSeq:   NC_000007.13 NT_007914.15
Ensembl:   ENSG00000106144
Entrez:   835
Chromosome Mapping:   7q34-q35

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