PrimePCR™ SYBR® Green Assay: FLNA, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Recommended - best efficiency

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0010844
Assay Design:   Intron-spanning
Chromosome Location:   X:153579367-153580265question
Amplicon Length:   142
Splice Variants Targeted:   ENST00000360319 ENST00000369850 ENST00000344736 ENST00000422373 ENST00000369852 ENST00000369856

Gene Information

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins transmembrane receptor complexes and second messengers. Defects in this gene are a cause of several syndromes including periventricular nodular heterotopias (PVNH1 PVNH4) otopalatodigital syndromes (OPD1 OPD2) frontometaphyseal dysplasia (FMD) Melnick-Needles syndrome (MNS) and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq Mar 2009]

Gene Symbol:   FLNA
Gene Name:   filamin A, alpha
Aliases:   ABP-280, ABPX, CVD1, DKFZp434P031, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD
RefSeq:   NC_000023.10 NG_008677.1 NG_011506.1 NT_167198.1
Ensembl:   ENSG00000196924
Entrez:   2316
Chromosome Mapping:   Xq28

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