PrimePCR™ SYBR® Green Assay: LMNB1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCIP0029571

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0014822
Assay Design:   Intron-spanning
Chromosome Location:   5:126145954-126147514question
Amplicon Length:   109
Splice Variants Targeted:   ENST00000261366 ENST00000395354

Gene Information

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability chromatin structure and gene expression. Vertebrate lamins consist of two types A and B. This gene encodes one of the two B type proteins B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). [provided by RefSeq Oct 2010]

Gene Symbol:   LMNB1
Gene Name:   lamin B1
Aliases:   ADLD, LMN, LMN2, LMNB, MGC111419
RefSeq:   NC_000005.9 NG_008360.2 NT_034772.6
Ensembl:   ENSG00000113368
Entrez:   4001
Chromosome Mapping:   5q23.2

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