PrimePCR™ SYBR® Green Assay: STAT5A, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCEP0024348

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0002322
Assay Design:   Exonic
Chromosome Location:   17:40462531-40462628question
Amplicon Length:   68
Splice Variants Targeted:   ENST00000345506 ENST00000540577 ENST00000546010 ENST00000452307

Gene Information

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by and mediates the responses of many cell ligands such as IL2 IL3 IL7 GM-CSF erythropoietin thrombopoietin and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L) which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq Jul 2008]

Gene Symbol:   STAT5A
Gene Name:   signal transducer and activator of transcription 5A
Aliases:   MGF, STAT5
RefSeq:   NC_000017.10 NG_007370.1 NT_010783.15
Ensembl:   ENSG00000126561
Entrez:   6776
Chromosome Mapping:   17q11.2

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