PrimePCR™ SYBR® Green Assay: TNFRSF13C, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0002332
Assay Design:   Exonic
Chromosome Location:   22:42321225-42321326question
Amplicon Length:   72
Splice Variants Targeted:   ENST00000291232

Gene Information

B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also some SLE patients have increased levels of BAFF in serum. Therefore it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq Jul 2008]

Gene Symbol:   TNFRSF13C
Gene Name:   tumor necrosis factor receptor superfamily, member 13C
Aliases:   BAFF-R, BAFFR, CD268, CVID4, MGC138235
RefSeq:   NC_000022.10 NG_007579.1 NT_011520.12
Ensembl:   ENSG00000159958
Entrez:   115650
Chromosome Mapping:   22q13.1-q13.31

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