PrimePCR™ SYBR® Green Assay: LBP, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Recommended - best coverage

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0015538
Assay Design:   Intron-spanning
Chromosome Location:   20:36993377-36997642question
Amplicon Length:   63
Splice Variants Targeted:   ENST00000217407 ENST00000538599

Gene Information

The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid lipopolysaccharide (LPS) on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI) the encoded protein binds LPS and interacts with the CD14 receptor probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins including BPI plasma cholesteryl ester transfer protein (CETP) and phospholipid transfer protein (PLTP). Finally this gene is found on chromosome 20 immediately downstream of the BPI gene. [provided by RefSeq Jul 2008]

Gene Symbol:   LBP
Gene Name:   lipopolysaccharide binding protein
Aliases:   MGC22233
RefSeq:   NC_000020.10 NT_011362.10
Ensembl:   ENSG00000129988
Entrez:   3929
Chromosome Mapping:   20q11.23

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