PrimePCR™ SYBR® Green Assay: PLAUR, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCIP0031103

List Price:    $179.00
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PrimePCR™ PreAmp for SYBR® Green Assay: PLAUR, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: PLAUR, Human
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0017227
Assay Design:   Intron-spanning
Chromosome Location:   19:44160738-44169587question
Amplicon Length:   145
Splice Variants Targeted:   ENST00000339082 ENST00000340093 ENST00000221264

Gene Information

This gene encodes the receptor for urokinase plasminogen activator and given its role in localizing and promoting plasmin formation likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq Jul 2008]

Gene Symbol:   PLAUR
Gene Name:   plasminogen activator, urokinase receptor
Aliases:   CD87, U-PAR, UPAR, URKR
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000011422
Entrez:   5329
Chromosome Mapping:   19q13

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