PrimePCR™ SYBR® Green Assay: LEPR, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCIP0031759

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0018270
Assay Design:   Intron-spanning
Chromosome Location:   1:66036364-66038047question
Amplicon Length:   131
Splice Variants Targeted:   ENST00000349533 ENST00000371060 ENST00000371059 ENST00000371058 ENST00000344610 ENST00000406510

Gene Information

The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight) and is involved in the regulation of fat metabolism as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons however encode distinct proteins (PMID:9207021).[provided by RefSeq Nov 2010]

Gene Symbol:   LEPR
Gene Name:   leptin receptor
Aliases:   CD295, DKFZp686B1731, OBR
RefSeq:   NC_000001.10 NT_032977.9 NG_015831.1
Ensembl:   ENSG00000116678
Entrez:   3953
Chromosome Mapping:   1p31

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