PrimePCR™ SYBR® Green Assay: SPHK1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0004053
Assay Design:   Exonic
Chromosome Location:   17:74383678-74383832question
Amplicon Length:   125
Splice Variants Targeted:   ENST00000323374 ENST00000545180 ENST00000392496 ENST00000543830

Gene Information

The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P) a lipid mediator with both intra- and extracellular functions. Intracellularly S1P regulates proliferation and survival and extracellularly it is a ligand for cell surface G protein-coupled receptors. This protein and its product S1P play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory antiapoptotic and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Sep 2011]

Gene Symbol:   SPHK1
Gene Name:   sphingosine kinase 1
Aliases:   SPHK
RefSeq:   NC_000017.10 NT_010783.15
Ensembl:   ENSG00000176170
Entrez:   8877
Chromosome Mapping:   17q25.2

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