PrimePCR™ SYBR® Green Assay: BBC3, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0005081
Assay Design:   Exonic
Chromosome Location:   19:47724161-47724376question
Amplicon Length:   186
Splice Variants Targeted:   ENST00000449228 ENST00000300880 ENST00000341983 ENST00000439096

Gene Information

This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq Dec 2011]

Gene Symbol:   BBC3
Gene Name:   BCL2 binding component 3
Aliases:   FLJ42994, JFY1, PUMA
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000105327
Entrez:   27113
Chromosome Mapping:   19q13.3-q13.4

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