PrimePCR™ SYBR® Green Assay: FGB, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0034177
Assay Design:   Exonic
Chromosome Location:   4:155484191-155486982question
Amplicon Length:   86

Gene Information

The protein encoded by this gene is the beta component of fibrinogen a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading display vasoconstrictor and chemotactic activities and are mitogens for several cell types. Mutations in this gene lead to several disorders including afibrinogenemia dysfibrinogenemia hypodysfibrinogenemia and thrombotic tendency. [provided by RefSeq Jul 2008]

Gene Symbol:   FGB
Gene Name:   fibrinogen beta chain
Aliases:   MGC104327, MGC120405
RefSeq:   NC_000004.11 NT_016354.19 NG_008833.1
Ensembl:   ENSG00000171564
Entrez:   2244
Chromosome Mapping:   4q28

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