PrimePCR™ SYBR® Green Assay: ITCH, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCEP0058417

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0057312
Assay Design:   exonic
Chromosome Location:   20:33095670-33095818question
Amplicon Length:   119
Splice Variants Targeted:   ENST00000374864 ENST00000262650 ENST00000535650

Gene Information

This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq Mar 2012]

Gene Symbol:   ITCH
Gene Name:   itchy E3 ubiquitin protein ligase homolog (mouse)
Aliases:   AIF4, AIP4, NAPP1, dJ468O1.1
RefSeq:   NC_000020.10 NG_023206.1 NT_011362.10
Ensembl:   ENSG00000078747
Entrez:   83737
Chromosome Mapping:   20q11.22

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