PrimePCR™ SYBR® Green Assay: ITGAV, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCIP0026077

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0006233
Assay Design:   Intron-spanning
Chromosome Location:   2:187503136-187506162question
Amplicon Length:   130
Splice Variants Targeted:   ENST00000261023 ENST00000374907 ENST00000433736 ENST00000544640

Gene Information

ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1356 and 8; 'ITGB1' 'ITGB3' 'ITGB5' 'ITGB6' and 'ITGB8') each can interact with extracellular matrix ligands; the alpha V beta 3 integrin perhaps the most studied of these is referred to as the Vitronectin receptor (VNR). In addition to adhesion many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq Feb 2009]

Gene Symbol:   ITGAV
Gene Name:   integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
Aliases:   CD51, DKFZp686A08142, MSK8, VNRA
RefSeq:   NC_000002.11 NT_005403.17
Ensembl:   ENSG00000138448
Entrez:   3685
Chromosome Mapping:   2q31-q32

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