PrimePCR™ SYBR® Green Assay: PRKCE, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0010787
Assay Design:   Intron-spanning
Chromosome Location:   2:46231711-46234640question
Amplicon Length:   77
Splice Variants Targeted:   ENST00000306156 ENST00000394874

Gene Information

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions such as neuron channel activation apoptosis cardioprotection from ischemia heat shock response as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq Jul 2008]

Gene Symbol:   PRKCE
Gene Name:   protein kinase C, epsilon
Aliases:   MGC125656, MGC125657, PKCE, nPKC-epsilon
RefSeq:   NC_000002.11 NT_022184.15
Ensembl:   ENSG00000171132
Entrez:   5581
Chromosome Mapping:   2p21

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