PrimePCR™ SYBR® Green Assay: WASL, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Recommended - best coverage

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0011623
Assay Design:   Intron-spanning
Chromosome Location:   7:123346417-123349217question
Amplicon Length:   143
Splice Variants Targeted:   ENST00000223023 ENST00000536685

Gene Information

The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli and interact with multiple proteins. Recent studies have demonstrated that these proteins directly or indirectly associate with the small GTPase Cdc42 known to regulate formation of actin filaments and the cytoskeletal organizing complex Arp2/3. The WASL gene product is a homolog of WAS protein however unlike the latter it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly and induce formation of long actin microspikes. [provided by RefSeq Jul 2008]

Gene Symbol:   WASL
Gene Name:   Wiskott-Aldrich syndrome-like
Aliases:   DKFZp779G0847, MGC48327, N-WASP, NWASP
RefSeq:   NC_000007.13 NT_007933.15
Ensembl:   ENSG00000106299
Entrez:   8976
Chromosome Mapping:   7q31.3

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