PrimePCR™ SYBR® Green Assay: CHRNA3, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0015061
Assay Design:   Intron-spanning
Chromosome Location:   15:78894432-78909405question
Amplicon Length:   185
Splice Variants Targeted:   ENST00000348639 ENST00000326828

Gene Information

This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq Nov 2009]

Gene Symbol:   CHRNA3
Gene Name:   cholinergic receptor, nicotinic, alpha 3
Aliases:   LNCR2, MGC104879, NACHRA3, PAOD2
RefSeq:   NC_000015.9 NG_023328.1 NT_010194.17 NG_016143.1
Ensembl:   ENSG00000080644
Entrez:   1136
Chromosome Mapping:   15q24

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