PrimePCR™ SYBR® Green Assay: Cldn5, Mouse

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qMmuCEP0031923

List Price:    $179.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qMmuCED0001017
Assay Design:   Exonic
Chromosome Location:   16:18777781-18777883question
Amplicon Length:   73
Splice Variants Targeted:   ENSMUST00000043577

Gene Information

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a critical component of endothelial tight junctions that control pericellular permeability. The knockout mice lacking this gene died within 10 h of birth and the blood-brain barrier in these mice against small molecules was selectively affected. This gene is expressed strongly in endothelium of normal lung and plays a regulation role during acrolein-induced acute lung injury. [provided by RefSeq Aug 2010]

Gene Symbol:   Cldn5
Gene Name:   Claudin 5
Aliases:   AI854493, MBEC1, Tmvcf
RefSeq:   NC_000082.6 NT_039624.8 NT_187008.1
Ensembl:   ENSMUSG00000041378
Entrez:   12741
Chromosome Mapping:   16 A3|16 11.65 cM

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