PrimePCR™ SYBR® Green Assay: Trp53, Mouse

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qMmuCIP0032520

List Price:    $179.00
Your Price:   Log In
 
Add to Custom Plate

Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qMmuCID0006264
Assay Design:   Intron-spanning
Chromosome Location:   11:69580402-69587378question
Amplicon Length:   195
Splice Variants Targeted:   ENSMUST00000005371 ENSMUST00000108657 ENSMUST00000108658 ENSMUST00000171247

Gene Information

This gene encodes tumor protein p53 which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines where it's believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation DNA-binding and oligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion and thus function as a tumor suppressor. Mice deficient for this gene are developmentally normal but are susceptible to spontaneous tumors. Evidence to date shows that this gene contains one promoter in contrast to alternative promoters of the human gene and transcribes a few of splice variants which encode different isoforms although the biological validity or the full-length nature of some variants has not been determined. [provided by RefSeq Jul 2008]

Gene Symbol:   Trp53
Gene Name:   Transformation related protein 53
Aliases:   Tp53, bbl, bfy, bhy, p44, p53
RefSeq:   NC_000077.6 NT_096135.6
Ensembl:   ENSMUSG00000059552
Entrez:   22059
Chromosome Mapping:   11 B2-C|11 39.0 cM

[ Close ]
Click here to print
[ Close ]
Click here to print
 

undefined

undefined

My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

undefined

undefined

undefined

undefined

undefined

undefined

undefined

undefined