PrimePCR™ SYBR® Green Assay: PRKCZ, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCIP0040542

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0037819
Assay Design:   Intron-spanning
Chromosome Location:   1:2077469-2080342question
Amplicon Length:   81
Splice Variants Targeted:   ENST00000378567 ENST00000400921 ENST00000461106 ENST00000461465 ENST00000470596 ENST00000496325 ENST00000482686 ENST00000486681 ENST00000470986 ENST00000470511 ENST00000471018 ENST00000497183 ENST00000400920

Gene Information

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   PRKCZ
Gene Name:   protein kinase C, zeta
Aliases:   PKC-ZETA, PKC2
RefSeq:   NC_000001.10 NT_004350.19
Ensembl:   ENSG00000067606
Entrez:   5590
Chromosome Mapping:   1p36.33-p36.2

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