PrimePCR™ SYBR® Green Assay: CASP8, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCEP0024229

List Price:    $179.00
Your Price:   Log In
Quantity:  
 
Add to Custom Plate

PrimePCR™ PreAmp for SYBR® Green Assay: CASP8, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: CASP8, Human
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0001959
Assay Design:   Exonic
Chromosome Location:   2:202131251-202131399question
Amplicon Length:   119
Splice Variants Targeted:   ENST00000392263 ENST00000432109 ENST00000264275 ENST00000440732 ENST00000392258 ENST00000447616 ENST00000358485 ENST00000413726 ENST00000323492 ENST00000429881 ENST00000264274 ENST00000392261 ENST00000392259 ENST00000392266

Gene Information

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain a large protease subunit and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described although not all variants have had their full-length sequences determined. [provided by RefSeq Jul 2008]

Gene Symbol:   CASP8
Gene Name:   caspase 8, apoptosis-related cysteine peptidase
Aliases:   ALPS2B, CAP4, Casp-8, FLICE, FLJ17672, MACH, MCH5, MGC78473
RefSeq:   NC_000002.11 NT_005403.17 NG_007497.1
Ensembl:   ENSG00000064012
Entrez:   841
Chromosome Mapping:   2q33-q34

[ Close ]
Click here to print
[ Close ]
Click here to print
 

undefined

undefined

My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

undefined

undefined

undefined

undefined

undefined

undefined

undefined

undefined